控制战略和控制机制,以减少卫星液滴的减少
1Tianjin Key Laboratory of Refrigeration Technology, Tianjin University of Commerce, Tianjin 300134, China; School of Energy and Environmental Engineering, Hebei University of Technology, Tianjin 300401, China.
International journal of pharmaceutics
|July 15, 2023
概括
医药和食品生产中的卫星液滴被新的排水辅助滴滴器 (DAD) 减少. 这种设备显著减少了卫星液滴的体积和大小,改善了单分散颗粒的形成.
科学领域:
- 流体动力学 流体动力学
- 材料科学 材料科学 材料科学
- 化学工程是化学工程的重要组成部分.
背景情况:
- 卫星滴对药物和食品中的单分散颗粒形成产生负面影响.
- 控制卫星滴滴的形成对于药丸制备等应用至关重要.
研究的目的:
- 开发和评估一种用于减少卫星滴滴的新型装置.
- 为了研究卫星滴水减少背后的机制.
主要方法:
- 引入一个带有中心不钢针的排水辅助滴水器 (DAD).
- 使用DAD和通用滴水器 (GD) 对滴水形成的实验和数值分析.
主要成果:
- DAD显著减少了卫星滴滴数量和体积 (87%的减少).
- DAD降低了初级滴滴大小,并增加了滴滴之间的间隔.
- DAD改变了流动模式,导致细丝较短,液体体积减少.
结论:
- DAD是一种有效的设备,可以最大限度地减少卫星滴.
- DAD显示出在制药,食品,农业和制造业应用的巨大潜力.
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