体重指数和对儿科脏健康的影响:用尿路生物标志物的横截面研究
T D K S C Gunasekara1, P Mangala C S De Silva2, E P S Chandana3
1Department of Zoology, Faculty of Science, University of Ruhuna, Matara, 81000, Sri Lanka.
Pediatric nephrology (Berlin, Germany)
|July 15, 2023
概括
这项研究没有发现强有力的证据将体重指数 (BMI) 与斯里兰卡学生的功能改变联系起来. 然而,严重瘦的女孩的营养不良可能与异常的脏健康结果有关.
科学领域:
- 儿科脏病学 儿科脏病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 肥胖和极度不健康的体重与慢性脏疾病有关.
- 与体重相关的儿科脏健康结果需要进一步调查.
- 了解这些关联对于公共卫生倡议至关重要.
研究的目的:
- 为了评估斯里兰卡学校学生的体重指数 (BMI).
- 评估BMI和脏健康生物标志物之间的关联.
- 为了确定儿科患者群体的潜在风险.
主要方法:
- 对1078名学生 (11-18岁) 的横截面研究.
- 用性别和年龄特定百分位数将BMI分为五个组进行分类.
- 尿路生物标志物的测量:KIM-1,NGAL和ACR.
主要成果:
- 在BMI组之间,尿液NGAL,ACR或KIM-1水平没有显著差异.
- 在严重瘦的女孩中发现BMI和KIM-1/NGAL之间的中等相关性.
- 尿损伤分子 (KIM-1) 显示没有显著的BMI关联.
结论:
- 在被研究的儿科患者群体中,没有强有力的证据表明BMI相关的功能改变.
- 潜在的异常脏健康结果与严重瘦女孩的营养不良有关.
- 需要进一步的研究来了解斯里兰卡的营养状况和儿科脏健康状况.
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