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Updated: Jul 23, 2025

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LRRK2的酸化状态和激酶活性以Rab8a/Rab10依赖的方式调节 (宏) 自

Elżbieta Kania1,2,3, Jaclyn S Long1,2, David G McEwan1,2

  • 1Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.

Cell death & disease
|July 15, 2023
PubMed
概括

富含白的重复激酶2 (LRRK2) 酸化位调节自. 损坏的LRRK2酸化破坏了细胞废物清除,通过增加激酶活性,促进帕金森病的病理学.

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