相关实验视频
Updated: Jul 23, 2025

07:27
Olfactory Assays for Mouse Models of Neurodegenerative Disease
Published on: August 25, 2014
22.1K
关于嗅觉功能障碍的立场论文:2023年
K L Whitcroft1,2,3, A Altundag4, P Balungwe5,6
1Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Rhinology
|July 16, 2023
概括
这份更新的立场论文涉及嗅觉功能障碍 (OD) 诊断和管理,包括最近的研究和COVID-19的影响. 它提供了关于术语,成像和特定OD类型的新建议,以提高研究的一致性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
背景情况:
- 随着COVID-19大流行,人们对嗅觉功能障碍 (OD) 的重大个人和社会负担的认识提高了.
- 越来越多的公众和科学家认识到嗅觉对生活质量,营养,社会互动和心理健康的影响.
- 自2017年关于嗅觉功能障碍的立场文件 (PPOD-17) 以来,关于OD的基础,翻译和临床研究取得了重大进展.
研究的目的:
- 介绍和讨论用于诊断和治疗嗅觉功能障碍的当前证据.
- 根据最近的研究和COVID-19大流行影响,更新建议.
- 促进一种共同的语言,提高嗅觉领域的研究质量和普遍性.
主要方法:
- 审查和综合有关嗅觉功能障碍的现有证据.
- 通过经过修改的Delphi流程开发更新的建议,涉及所有共同作者.
- 包含了新的章节,解决了定性OD和COVID-19相关的OD.
主要成果:
- 主要更新包括对嗅觉术语和成像的修订建议.
- 新的部分专门针对定性嗅觉功能障碍和COVID-19相关的嗅觉功能障碍.
- 管理部分已更新,以反映最新的证据和临床实践.
结论:
- 提供了当前证据和专家一致建议的概述,用于定义,调查和管理OD.
- 旨在鼓励临床医生和研究人员采用标准化的术语和实践.
- 预期的结果是提高嗅觉功能障碍研究的方法质量,一致性和通用性.
相关概念视频
Olfactory Receptors: Location and Structure
9.4K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.4K
Physiology of Smell and Olfactory Pathway
8.8K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
8.8K
Olfaction
44.5K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
44.5K
Taste Buds and Receptors
2.3K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
2.3K

