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Updated: Jul 23, 2025

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脂脂质体脂质体对片 (106-128) 粉样蛋白形成的影响

Deepika Regmi1, Fengyun Shen1, Aleksander Stanic1

  • 1Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA.

Biochimica et biophysica acta. Biomembranes
|July 16, 2023
PubMed
概括

子蛋白 (PrP) 聚合是子疾病的关键. 这项研究表明,脂质体的组成和电荷对PrP106-128) 聚合具有关键影响,为开发抑制剂提供了洞察力.

关键词:
聚合是一种聚合.粉样蛋白是什么 粉样蛋白是什么脂质细胞体中的脂肪体.脂酸是一种脂酸.普里昂 (Prion) 是一个子.

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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