在液体染色学和毛细血管电泳术中用于分离液体的奇拉离子液体的最新发展:一篇综述
Huifeng Liu1, Jia Chen2, Mingli Chen3
1Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.
Analytica chimica acta
|July 16, 2023
概括
基拉尔离子液体 (CILs) 在HPLC和CE中增强了反体分离. 本综述涵盖了CIL应用,机制和未来在性染色学和毛细血管电泳分析中的前景.
科学领域:
- 分析化学 分析化学
- 分离科学 分离科学
背景情况:
- 离子液体 (ILs) 是100°C以下的盐,具有低蒸气压和高热稳定性等理想性质.
- 性离子液体 (CIL) 在各种分析技术中为反体分离提供了独特的优势.
研究的目的:
- 审查CILs在高性能液体染色学 (HPLC) 和毛细管电泳 (CE) 中用于反体分离的最新应用.
- 通过CILs阐明基因分离的背后机制.
- 讨论CIL在合性LC和CE的未来前景.
主要方法:
- 文献综述,重点关注过去五年发表的研究.
- 分析CILs作为HPLC中性静止相 (CSP) 和移动相添加剂.
- 在CE中检查CIL作为背景电解质添加剂 (BGE),性联结体和性选择体 (CSs).
主要成果:
- 在HPLC和CE两种方法中,CIL已经显示出异构分离效率的显著改善.
- 突出了CIL的各种作用,包括CSP,移动相添加剂,BGE添加剂和性选择器.
- 系统地解释了使用CILs进行enantioseparation的机制.
结论:
- CIL是用于奇拉分离的多功能工具,提供可调节的特性以提高性能.
- 该综述提供了CIL应用程序的全面概述,以及它们在推进奇拉分析方面的潜力.
- 对LC和CE中的CIL的未来研究方向有望开发更有效的抗分离方法.
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