精准医学在医疗保健中的应用 - - 欧洲视角
Albrecht Stenzinger1,2, Ejner K Moltzen3, Eva Winkler4
1Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Journal of internal medicine
|July 16, 2023
概括
精准医学 (PM) 使用基因组测试来定制治疗. 实施PM需要医疗保健,学术界,政策制定者,行业和患者之间的合作,以实现可持续的生态系统.
科学领域:
- 基因组学和生物信息学
- 翻译医学是一种翻译医学.
- 卫生政策 卫生政策
背景情况:
- 高通量测序和向疗法推动了向个性化医学 (PM) 的转变.
- 通过全面的基因组测试,PM提供了更有效的治疗方法,副作用更少.
- 欧洲国家正在采用国家战略或自下而上的倡议来实施PM.
研究的目的:
- 总结关于在欧洲建立可持续的PM治理和组织的关键经验.
- 讨论PM实施的关键的伦理,法律和数据访问方面.
- 突出需要改善补偿,教育和患者参与的需要.
主要方法:
- 审查欧洲国家和地区的PM实施战略.
- 分析治理,组织,道德和法律方面的考虑.
- 讨论通过真实世界的数据和临床试验来产生证据.
主要成果:
- 成功实施PM需要基于医疗保健系统组织的量身定制方法 (自上而下与自下而上).
- 关键的推动因素包括强大的治理,跨学科教育,患者参与,以及对现实世界的数据的访问.
- 解决道德,法律和退款方面的挑战对于公平获取和可持续性至关重要.
结论:
- 精准医学代表了医疗保健的范式转变,需要现代化的协作生态系统.
- 参与所有利益相关者 - 医疗保健,学术界,政策制定者,行业和患者 - 对于成功的系统转型至关重要.
- 一种可持续的,非隔离的准确医疗保健方法有利于患者和社会.
关键词:
临床试验是指临床试验中的临床试验.教育和培训的教育和培训.伦理和法律方面的问题治理 治理 治理 治理 治理 治理患者倡导 患者倡导个性化医疗是个性化的医疗.精准医学是一门精准医学.现实世界的证据.更多相关视频
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