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代谢功能障碍相关的胆结石疾病:期望更多的关键护理表现
Piero Portincasa1, Agostino Di Ciaula2, Leonilde Bonfrate2
1Clinica Medica "A. Murri", Division of Internal Medicine, Department of Preventive and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, p.zza Giulio Cesare 11, 70124, Bari, Italy. piero.portincasa@uniba.it.
胆结石影响全球20%的成年人,通常与胆固醇有关. 这种与代谢功能障碍相关的胆结石疾病与肥胖和糖尿病越来越常见.
科学领域:
- 胃肠病学和肝病学
- 代谢疾病 代谢疾病
背景情况:
- 胆结石,固体胆树具体物,影响全球20%的成年人.
- 胆结石病影响需要医疗或手术干预的患者,在西方医院中很常见.
- 胆固醇胆结石在西方国家普遍存在,是由于胆固醇平衡受损而产生的.
研究的目的:
- 审查胆结石的关键病原性和临床方面.
- 为了突出胆结石作为代谢功能障碍的结果.
- 在全球日益增加的代谢疾病的背景下讨论胆结石.
主要方法:
- 关于胆结石病原性和临床方面的文献综述.
- 分析胆固醇胆结石与代谢功能障碍之间的联系.
- 讨论胆结石作为一种与代谢功能障碍相关的疾病.
主要成果:
- 胆结石由胆固醇单水合物晶体,粘素,胆酸和蛋白质聚合物组成.
- 在西方国家,大约80%的胆结石是基于胆固醇的.
- 胆固醇胆结石发生率与胰岛素抵抗,2型糖尿病,肥胖和代谢综合征相关.
结论:
- 胆结石是一个重要的公共卫生问题,特别是在西方国家.
- 胆结石可以被视为代谢功能障碍相关疾病的表现.
- 与代谢功能障碍相关的胆结石病需要具体的预防策略.
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