用不同的新鲜气流对老年患者认知功能的麻醉管理的影响:一项随机双盲研究
Bilge Özge Kılıç1, Meltem Savran Karadeniz1, Emre Şentürk1
1Department of Anaesthesiology and Reanimation, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
Turkish journal of anaesthesiology and reanimation
|July 17, 2023
概括
最小流量麻醉 (0.5 L min-1) 和中流量麻醉 (2 L min-1) 在老年患者中显示出类似的恢复和认知功能结果. 这两种新鲜气体流都可以在适当的监控下安全地使用.
科学领域:
- 麻醉学 麻醉学
- 老年医学 老年医学
- 神经科学是一个神经科学.
背景情况:
- 新鲜气流 (FGF) 是麻醉治疗中的一个关键参数.
- 优化FGF对于患者的康复和认知功能至关重要,特别是在老年人中.
- 最小流量麻醉 (0.5 L min-1) 和中流量麻醉 (2 L min-1) 代表了FGF管理的不同方法.
研究的目的:
- 为了比较两个不同的新鲜气流 (FGF) 对麻醉恢复的影响.
- 在不同的FGF条件下评估老年患者的早期认知功能.
- 为了确定最小流量与中流量麻醉在老年人的安全性和有效性.
主要方法:
- 这是一项前性,随机,双盲研究,涉及60名老年患者.
- 在维护期间,患者被分配给接受最小流量 (0.5 L min-1 FGF) 或中流量 (2 L min-1 FGF) 麻醉.
- 记录了恢复时间,并使用阿登布鲁克的认知检查 (ACE-R) 在术前和术后评估认知功能.
主要成果:
- 在两个FGF组之间,在人口特征或整体恢复时间方面没有发现显著差异.
- 在手术前,第一次和第三次手术后的几天里,ACE-R得分在两组之间没有显著差异.
- 与手术前的基线相比,在中流组的第三个术后一天,ACE-R得分和记忆子得分显著下降.
结论:
- 在老年患者的康复和认知功能方面,最小流动麻醉并不优于中流动麻醉.
- 随着适当的监测,可以安全地进行最小和中流麻醉,而不会对恢复和认知产生不良影响.
- 建议仔细监测,考虑到潜在的低氧化和麻醉水平变化与减少的FGF.
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