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Updated: Jul 23, 2025

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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反应性星球细胞的动力学促进了cuprizone诱导的脱髓化后的组织再生

Lara-Jasmin Schröder1,2,3, Felix Mulenge2, Andreas Pavlou2

  • 1Department of Neurology, Hannover Medical School, Hannover, Germany.

Glia
|July 17, 2023
PubMed
概括

中枢神经系统 (CNS) 中的反应性星球细胞在脱髓化和复髓化过程中表现出动态变化. 这些细胞与微质细胞广泛沟通,影响神经炎症和复发性硬化症 (MS) 等疾病的修复过程.

关键词:
里博的标签 里博Tag星球细胞是星球细胞.这就是cuprizone.脱化是脱化的一种.多发性硬化症多发性硬化症复黄化是复黄化的一种.

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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