身体质量指数和中国老年人全因死亡风险:基于CLHLS数据的经验性队列研究
Yun Wang1, Xuekui Liu2, Tongneng Xue1
1The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu, China.
Preventive medicine reports
|July 17, 2023
概括
在中国老年人中,较高的体重指数 (BMI) 与较低的全因死亡率有关,特别是在没有2型糖尿病的人中. 这表明肥胖在这个群体中可能是保护性的.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 老年人群体质量指数 (BMI) 和死亡率之间的关系需要进一步研究,特别是在不同的种族群体内.
- 了解这些关联对于制定有针对性的卫生干预措施和公共卫生战略至关重要.
研究的目的:
- 检查中国老年人群体质量指数 (BMI) 与全因死亡率之间的关联.
- 根据2型糖尿病的存在或不存在来探索这种关系中的潜在差异.
主要方法:
- 分析了13319名中国老年人 (2008-2018) 的队列.
- 根据BMI,参与者被分为体重不足,体重正常和超重/肥胖的组.
- 考克斯比例危险回归和受限立方线回归被用来评估BMI与死亡率的关联.
主要成果:
- 与超重/肥胖个体相比,低体重和正常体重个体的死亡风险较高 (HR分别为1.213和1.104).
- 在非2型糖尿病患者中观察到BMI和死亡率之间的非线性反向关系 (肥胖悖论).
- 2型糖尿病患者在BMI和死亡率之间表现出U形的关联.
结论:
- 肥胖可能会对中国老年人没有2型糖尿病的全因死亡率产生保护作用.
- 糖尿病患者和非糖尿病患者的老年人群之间,BMI与死亡率的关系有显著差异,这凸显了对量身定制的健康评估的需要.
相关概念视频
Obesity
542
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
542
Life Tables
131
A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...
131
Bone Disorders
3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K


