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肥胖症:流行病学,病理生理学,心血管疾病,死亡率和管理
Shibo Wei1, Thanh T Nguyen2, Yan Zhang1
1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.
Frontiers in endocrinology
|July 17, 2023
概括
标记性肥胖症的特点是肌肉损失和脂肪积累,增加了脆弱,心血管疾病和死亡的风险,特别是在老年人中. 为了更好的定义和治疗,需要进一步的研究.
科学领域:
- 老年学是一门学科.
- 代谢障碍 代谢障碍 代谢障碍
- 心血管健康的心血管健康
背景情况:
- 肥胖症涉及同时存在的肌肉损失和多余的身体脂肪.
- 这种情况与脆弱性,残疾和死亡率的增加有关.
- 老年人特别容易患上sarcopenic肥胖症.
研究的目的:
- 审查目前关于sarcopenic肥胖症的知识.
- 探索其与心血管疾病的关联.
- 检查其对所有原因死亡率的影响.
主要方法:
- 关于sarcopenic肥胖症的文献综述.
- 分析与心血管疾病标志物的关联.
- 检查与sarcopenic肥胖相关的死亡率数据.
主要成果:
- 标本性肥胖与包括心血管疾病在内的重大健康风险有关.
- 这种情况有助于增加全因死亡率.
- 缺乏统一的定义阻碍了流行研究和有针对性的干预措施.
结论:
- 肥胖症 (sarcopenic obesity) 是一个主要的健康问题,特别是在老年人群中.
- 改善对病原体的定义和理解对于更好的治疗策略至关重要.
- 需要进一步的研究来解决肥胖,肌肉损失和相关健康结果的复杂相互作用.
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