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Updated: Jul 23, 2025

Evaluating the Differentiation Capacity of Mouse Prostate Epithelial Cells Using Organoid Culture
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前列腺癌的血统可塑性和治疗耐药性:遗传学,表观遗传学和进化学的交叉点

Jarrell Imamura1, Shinjini Ganguly1, Andrew Muskara1

  • 1Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, United States.

Frontiers in endocrinology
|July 17, 2023
PubMed
概括

阴道抗性前列腺癌 (CRPC) 可以演变为神经内分泌前列腺癌 (NEPC),失去雄激素受体 (AR) 的依赖. 这种血统可塑性是由遗传和表观遗传变化驱动的,需要针对这些机制的新型治疗策略.

关键词:
表观遗传失调是指表观遗传失调的表观遗传失调.荷尔蒙疗法耐药性 荷尔蒙治疗耐药性血统的可塑性 血统的可塑性神经内分泌前列腺癌前列腺癌.无线电电阻的使用方法

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