关于艾滋病毒感染男性获得性阴性腺的最新情况:病变发生,诊所和治疗
Sara De Vincentis1,2,3, Vincenzo Rochira1,2
1Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Frontiers in endocrinology
|July 17, 2023
概括
阴性腺缺陷症在艾滋病毒感染的男性 (MLWH) 中很常见,通常比一般人群更早出现. 虽然治疗得到了改进,但与整体健康相关的功能性阴性腺症需要个性化护理,平衡丸激素治疗与生活方式干预.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 男人的健康 男人的健康
背景情况:
- 低雄性恋在感染艾滋病毒的男性 (MLWH) 中普遍存在,比未感染艾滋病毒的男性更早发生.
- 尽管医学取得了进步,但阴性腺体缺陷症影响了20-60岁的MLWH的13%-40%.
- 低 (T) 的症状是非特异性的,并与艾滋病毒感染重叠,在没有实验室检测的情况下,有潜在的诊断风险.
研究的目的:
- 审查目前关于MLWH中阴性腺体缺陷症的知识.
- 探索导致丸激素水平下降的因素.
- 为临床方法和个性化治疗提供指导.
主要方法:
- 这是一个叙事评论.
- 它综合了MLWH中低性体现现有的证据.
- 它讨论了病因因素,临床表现和治疗策略.
主要成果:
- 新出现的证据表明,MLWH的功能性阴性腺症受健康状况,并发症和艾滋病毒相关因素的影响.
- 生活方式的改变在理论上是有益的,但缺乏强有力的证据来正常化T水平.
- 当非药物方法失败时,丸激素疗法仍然是功能性阴性双胞胎症的选择.
结论:
- 在MLWH中治疗阴性腺症需要修订,考虑到其功能性质.
- 个性化治疗应优先优化非淋巴结合性并发症.
- 衡量补充的益处和风险至关重要,以避免过度治疗.
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