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Updated: Jul 23, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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对CD22分子的结合域有助于T细胞参与双特异性抗体的生物活性

Jie Chen1, Zhidi Pan1, Lei Han2

  • 1Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.

Heliyon
|July 17, 2023
PubMed
概括

通过考虑抗体狂热度和结合域,优化针对CD22的T细胞参与双特异性抗体 (TCBs) 显著提高了它们在治疗B细胞恶性瘤中的有效性. 这种方法改善了抗瘤活性,提供了一个有前途的治疗策略.

关键词:
贪 贪 是一种贪.具有约束力的域名在CD2222中,我们可以看到CD22.参与T细胞的双特异性抗体.

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