在患有肺癌的患者中区分恶性和良性流:一个F-FDG PET/CT追溯性研究
Weishan Zhang1, Zhe Liu2, Xiaoyi Duan1
1PET/CT Department of the First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Frontiers in oncology
|July 17, 2023
概括
在肺癌患者中,18F-氧葡萄糖正子发射断层扫描/计算机断层扫描 (18F-FDG PET/CT) 有效地区分了恶性多发性溢出与良性多发性溢出. 结合肺部SUVmax,淋巴结大小和性别,可以提供高诊断准确度.
科学领域:
- 在瘤学瘤学.
- 核医学就是核医学.
- 放射学 放射学是一门学科.
背景情况:
- 区分恶性流 (MPE) 和良性流 (BPE) 对于肺癌患者的治疗至关重要.
- 准确的差异化影响治疗策略和患者预后.
- 目前的诊断方法可能是侵入性的,可能有局限性.
研究的目的:
- 评估18F-氧葡萄糖正子发射断层扫描/计算机断层扫描 (18F-FDG PET/CT) 在肺癌患者中区分MPE和BPE的临床实用性.
- 确定成像特征和预测MPE的临床因素.
主要方法:
- 追溯分析18F-FDG PET/CT数据,来自237名肺癌患者,在8年内发生了多发性溢液.
- 胸腔溢出性质通过细胞学或活检证实.
- 统计分析包括比较,多重回归和ROC曲线分析,以评估诊断性能.
主要成果:
- 与BPE (n=67) 相比,MPE (n=170) 呈现出较高的多体SUVmax和更厚的多体.
- MPE与非小细胞肺癌,外周瘤和女性性别相关.
- 对MPE的独立风险因素包括多体SUVmax,性别和中枢淋巴结大小,产生高诊断性能 (AUC=0.989).
结论:
- 集成的18F-FDG PET/CT成像是一种有价值的非侵入性工具,用于在肺癌中区分MPE和BPE.
- 结合多SUVmax,胸部淋巴结特征和患者的性别,可以提高MPE的诊断准确性.
更多相关视频
10:28Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
11.2K
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
18.9K
相关概念视频
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
116
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
116
01:29Positron Emission Tomography
4.3K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.3K
01:28Pleural Effusion II: Symptoms and Management
218
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
218