高血压和肥胖对左心房相位功能的相互作用作用:一个三维心声回声学研究
Rui Zhang1, Cunying Cui1, Shuojing Wang1
1Department of Ultrasound, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Quantitative imaging in medicine and surgery
|July 17, 2023
概括
高血压和肥胖严重损害左心房功能,它们的联合存在加剧了这种影响. 减肥对于高血压患者的心血管健康至关重要.
科学领域:
- 心脏病学 心脏病学
- 心血管生理学心血管生理学
- 肥胖医学 肥胖医学
背景情况:
- 高血压 (HT) 和肥胖是普遍存在的疾病,通常是并存的.
- 无论是HT还是肥胖,都独立地导致左心房 (LA) 功能障碍.
- 了解它们对LA功能的综合影响对于心血管健康至关重要.
研究的目的:
- 为了比较不同BMI类别的高血压和非高血压个体的LA功能.
- 研究HT和肥胖对LA功能的相互作用效应.
- 为了确定受HT和BMI相互作用影响的特定LA参数.
主要方法:
- 一项涉及258名参与者的横截面研究 (145名高血压患者,113名非高血压患者).
- 参与者按BMI分类为正常体重,超重和肥胖群体.
- 使用三维心声谱评估的左心房 (LA) 体积和应变参数.
主要成果:
- 在多个参数中观察到HT和肥胖对LA功能的显著相互作用效应,包括LA射出分数和纵向菌株 (LASr,LAScd,LASct).
- 无论是HT还是增加的BMI都与LA菌株参数有负相关.
- 一个通用线性模型在调整混因子后证实了HT和肥胖对LA菌株的相互作用效应.
结论:
- 高血压和增加的体重指数 (BMI) 都会对左心房 (LA) 功能产生不利影响.
- 高血压和肥胖的共存协同影响LA的表现.
- 体重管理对于减轻高血压患者心血管风险至关重要.
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