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在COVID-19和非COVID-19患者之间对细菌感染进行比较研究,对不同隔离物及其抗生素敏感性模式进行比较

Nitali Arun¹, Kumar Saurabh¹, Sweta Muni¹

¹Microbiology, Indira Gandhi Institute of Medical Sciences, Patna, IND.

|July 17, 2023

概括

这项研究在COVID-19患者中确定了常见的细菌和真菌感染,揭示了高抗生素耐药性. 在SARS-CoV-2患者的二次感染管理中,最佳的抗微生物策略至关重要.

科学领域:

医学微生物学医学微生物学
传染性疾病传染性疾病
在COVID-19研究研究中.

背景情况:

随着SARS-CoV-2大流行,医疗保健系统的适应变得越来越必要,而抗微生物药物在COVID-19管理中发挥着潜在的作用.
在COVID-19患者中,鼻腔感染与增加的死亡率和疾病严重程度有关,这表明存在关键的知识差距.

研究的目的:

从COVID-19患者的各种样本中确定细菌分离物的光谱.
评估这些分离物的抗生素耐药性模式.
为了比较COVID-19和非COVID-19患者之间的隔离型和抗生素敏感性.

主要方法:

在帕特纳的IGIMS进行了六个月 (2021年2月至7月) 的观察性横截面研究.
使用标准细菌学程序分析了来自COVID-19患者的105个临床样本 (尿液,血液,,呼吸道).
根据临床和实验室标准研究所的指导方针进行的抗菌素敏感性测试.

主要成果:

最常见的分离物是克拉姆阴性细菌 (56.14%),其次是坎迪达 (26.31%) 和克拉姆阳性细菌 (17.54%).
大肠杆菌和Klebsiella pneumoniae是最常见的分离病原体.
观察到高耐药率:百分之百的安培西林在肠道细菌,和百分之百的西普罗夫洛克萨和 gentamicin 在Enterococcus spp.

结论:

二次细菌和真菌感染在COVID-19患者中很普遍,经常表现出显著的抗生素耐药性.
有效的抗菌药物管理计划对于指导基于微生物数据的经验性治疗选择至关重要.

关键词:

在AMR监控中,AMR监控对抗微生物的敏感性.一个图案的 ast 模式.在COVID-19中,有很多人.多重耐药性 (mdr) 是指多重耐药性

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