锡诺瓦克COVID-19高血压患者的副作用:巴基斯坦的一项观察性研究
Ahsan Masood1, Hira Khalid Chohan2, Muhammad Mubeen3
1Internal Medicine, Gomel State Medical University, Gomel, BLR.
Cureus
|July 17, 2023
概括
高血压在西诺瓦克COVID-19疫苗接种后显著增加了发烧和注射部位疼痛等副作用. 这些副作用通常是轻微和短暂的,影响了第一剂和第二剂.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 心脏病学 心脏病学
背景情况:
- 接种COVID-19疫苗的接受程度受到安全性和副作用的影响.
- 疫苗的副作用通常是轻微的,局部的和自我限制的.
- 了解特定人群中的副作用患病率对于疫苗的信心至关重要.
研究的目的:
- 评估Sinovac疫苗接种后副作用的发生率.
- 为了比较高血压和非高血压个体之间的副作用发生率.
- 为了确定对Sinovac疫苗的常见局部和全身反应.
主要方法:
- 这是一项涉及600名接受了Sinovac疫苗剂量的参与者的横截式多中心研究.
- 收集了有关局部和全身副作用的数据.
- 奇平方测试用于分析高血压和副作用之间的关联.
主要成果:
- 高血压与疫苗的副作用有显著的相关性 (p = 0.002).
- 第一个剂量后,发烧是最常见的副作用 (51.0%高血压 vs 20.7%非高血压,p < 0.001).
- 第二剂后,发烧也占主导地位 (36.0%高血压患者与19.0%非高血压患者,p < 0.001).
结论:
- 高血压是增加Sinovac疫苗副作用的可能性和严重性的重要因素.
- 发烧,注射部位疼痛和胀是最常见的副作用.
- 研究结果强调,需要在接种疫苗后对高血压患者进行量身定制的监测.
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