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营养状况与转移性脊柱瘤患者脊柱手术后的生存率有关

Masahiro Iinuma¹, Tsutomu Akazawa², Yoshiaki Torii³

¹Department of Orthopaedic Surgery, St. Marianna University, Yokohama Seibu Hospital, Yokohama, JPN.

|July 17, 2023

概括

通过JmGPS,CAR和PNI评估的手术前营养状况显著影响为转移性瘤进行脊柱手术的患者的存活率. 早期评估有助于预测患者的结果.

科学领域:

在瘤学瘤学.
神经外科神经外科
营养科学营养科学

背景情况:

营养状况是影响多学科治疗结果的已知因素.
转移性瘤脊椎手术后的营养状况和生存率之间的直接联系仍然未确立.
这项研究调查了营养标记在这个特定患者群体中的预测价值.

研究的目的:

评估手术前营养状况与转移性脊髓瘤患者的存活率之间的相关性.
为了确定特定的营养指数,可以预测脊髓手术后的生存结果.

主要方法:

使用日本版本的修改格拉斯哥预后分数 (JmGPS),C反应蛋白与白蛋白比率 (CAR),预后营养指数 (PNI),中性粒细胞与淋巴细胞比率 (NLR) 和血小板与淋巴细胞比率 (PLR) 评估营养状况.
数据来自57名患者的手术前实验室检测.
生存期定义为从手术前数据收集到死亡的时间.

主要成果:

CAR,JmGPS和PNI与生存时间有显著的相关性 (CAR和JmGPS的P<0.01,PNI的P=0.02).
具有0的JmGPS得分的患者经历了显著更长的生存期.
确定了预测90天 (≥0.880) 和180天 (≤0.220) 存活时间的最佳CAR截止值.

结论:

术前对JmGPS,CAR和PNI的评估对于估计脊髓转移瘤患者的营养状况是有价值的.
这些营养标志物可以有效地预测这个队列中脊髓手术后的生存率.
将这些评估纳入临床实践可能会改善患者管理和预后.

关键词:

转移性脊髓瘤转移性脊髓瘤营养状态营养状况患者的生存率患者的生存率预测得分系统的预测得分系统.进行手术治疗治疗.

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