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Updated: Jul 23, 2025

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通过高效的phi29 DNA聚合酶改进了单细胞基因组放大.

Jia Zhang1,2,3,4, Xiaolu Su1,2,3,4, Yefei Wang2,3,4,5

  • 1Single-Cell Center, CAS Key Laboratory of Biofuels, Shandong Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China.

Frontiers in bioengineering and biotechnology
|July 17, 2023
PubMed
概括

改进的单细胞基因组放大 (iSGA) 增强了单细胞测序的全基因组放大. 这种新方法提高了效率和覆盖范围,使大规模单细胞测序更容易获得和更具成本效益.

关键词:
GB1 聚变蛋白质的结合蛋白双硫化物键是一种二硫化物键.phi29 DNA聚合酶的使用工艺工程高效率phi29 DNA聚合酶一个单细胞的基因组放大.

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