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Updated: Jul 23, 2025

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基因修复的iPS细胞作为患有骨质不完美的患者的新方法

Agnieszka Fus-Kujawa1, Barbara Mendrek2, Karolina Bajdak-Rusinek1

  • 1Department of Medical Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.

Frontiers in bioengineering and biotechnology
|July 17, 2023
PubMed
概括

这项研究成功地使用诱导多能干细胞 (iPSC) 和一种新的恒星聚合物输送系统在骨质变异不完善 (OI) 患者细胞中修复了COL1A1基因突变,显示出高的修复和活力率.

关键词:
系统交付系统的交付系统.同类的重组组合.诱导多能干细胞的诱导干细胞.骨质发生不完美 (osteogenesis imperfecta) 是一个不完美的疾病.患者的特定细胞/基因疗法.重编程是重新编程.星星聚合物 星星聚合物

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