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Updated: Jul 23, 2025

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
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免疫调节纳米系统:用于治疗慢性伤口的先进交付工具

Xiangyu Chu1,2, Yuan Xiong1,2, Samuel Knoedler3,4

  • 1Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Research (Washington, D.C.)
|July 17, 2023
PubMed
概括

由于免疫反应受损,老龄化社会面临越来越多的慢性伤口 (CWs). 本综述探讨了免疫调节纳米系统作为先进的传递系统,以管理炎症并改善CW治愈结果.

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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