白天的嗜睡与较低的认知分数有关:展望未来的研究
K M Hayden1, A Anderson2, A P Spira3,4,5
1Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
JAR life
|July 17, 2023
概括
患有2型糖尿病的老年人频繁的白天嗜睡与随着时间的推移与较差的认知功能有关. 这突显了解决睡眠问题对风险人群大脑健康的重要性.
科学领域:
- 老年学是一门学科.
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
背景情况:
- 日间嗜睡在老年人中很普遍,通常是由于睡眠障碍导致的夜间睡眠不良而引起的.
- 这种嗜睡可能与这群人群的认知能力下降有关.
研究的目的:
- 调查自我报告的白天嗜睡和认知功能之间的关联.
- 在Look AHEAD临床试验的背景下研究了这种关系.
主要方法:
- 一项随机临床试验的观察后续研究涉及1,778名参与者 (45-76岁) 患有2型糖尿病和超重/肥胖.
- 在基线和12-13岁时评估自我报告的白天嗜睡,并在12-13岁和18-20岁时评估认知功能.
主要成果:
- 报告频繁白天嗜睡的参与者在认知综合评分上表现明显差.
- 在强化生活方式干预组中,频繁的白天嗜睡与数字符号编码和Trail Making Part-B的表现较差有关.
- 白天睡眠显示了与种族/种族,APOE ε4状态,心血管疾病史和抑郁症的统计相互作用.
结论:
- 长期白天嗜睡预测糖尿病和超重/肥胖的老年人认知表现较差.
- 这些发现强调了睡眠障碍与高风险个体的认知健康之间的联系.
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