沙特阿拉伯疹病例的临床和微生物学特征
Wala Alkhalifa1, Hassan Alhawaj1, Aisha Alamri2
1Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Infection and drug resistance
|July 17, 2023
概括
沙特阿拉伯的白病例显示出非白虫Candida物种的高发病率和显著的抗真菌耐药性. 关键的死亡因素包括年龄,COVID-19和托西利祖马布的使用,强调需要警监测.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
背景情况:
- кандидемия构成了严重的全球健康威胁,加上新兴的抗真菌耐药性.
- 了解当地流行病学和风险因素对于有效的患者管理至关重要.
研究的目的:
- 为了确定白血病的发病率,Candida物种的分布,以及死亡风险因素.
- 在沙特阿拉伯的一个学术机构分析Candida血液分离物的抗真菌易感性模式.
主要方法:
- 从2020年7月到2021年12月的候选性病例的前性审查.
- 使用微稀释进行抗真菌敏感性测试,以检测可纳,伏利可纳和其他物质.
- 确定30天死亡率的独立风险因素.
主要成果:
- 分析了43名患者的48个分离物;83%是ICU患者.
- 最常见的物种是Candida glabrata和Candida parapsilosis (每一个为22.9%).
- 39.3%的分离物体对至少一种抗真菌药物表现出耐药性;对可纳的耐药性为18%.
结论:
- 非白虫Candida物种的高患病率带来了治疗挑战.
- 显著的抗真菌耐药性需要持续监测和快速诊断工具.
相关概念视频
Fungal Phylum Microsporidia
42
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
42
Factors Affecting the Risk of Infection
12.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.0K
Sputum Studies II: Culture and Sensitivity
409
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
409


