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组织工程可食用鸟巢 (TeeBN)

Yu Liu1, Yangyang Liu1, Jiayue Liu1

  • 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.

International journal of bioprinting
|July 17, 2023
PubMed
概括
此摘要是机器生成的。

组织工程使用3D打印和细胞培养创造了可食用鸟巢 (EBN) 替代品. 这些新型TeeBN的营养益处与自然EBN的营养益处相当,安全性问题较低.

关键词:
通过3D打印打印3D打印.细胞农业 细胞农业可食用鸟类的.食品技术 食品技术 食品技术组织工程是组织工程.

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科学领域:

  • 生物技术是生物技术.
  • 组织工程是组织工程.
  • 食品科学 食品科学 食品科学

背景情况:

  • 可食用鸟巢 (EBN) 是东亚的美味,但过度采摘会引发生态和食品安全问题.
  • 传统的EBN收获面临着可持续性和污染挑战.

研究的目的:

  • 通过组织工程开发一种可持续和安全的替代天然EBN.
  • 创建组织工程可食用鸟巢 (TeeBNs),模仿自然EBNs的营养和生物特性.

主要方法:

  • 采用两层系统制造TeeBNs:一个由3D打印支架中的上皮细胞组成的养层和一个由食品级聚合物组成的接收层.
  • 封装上皮细胞以分泌生物活性化合物,如酸和EGF.
  • 用小鼠体外测定和体内代谢学研究进行表征.

主要成果:

  • 养层支持3D细胞生长和生物活性成分的分泌.
  • 接收层含有必需的营养素,并且缺乏天然EBN中常见的污染物.
  • 在体内研究表明,TeeBNs与天然EBNs具有类似的血清代谢物概况,表明具有可比的营养效应.

结论:

  • 一种新的组织工程方法成功地产生了EBN替代物 (TeeBNs).
  • TeeBNs复制自然EBN的代谢功能,同时减轻安全风险.
  • 这一创新为通过实验室细胞培养和3D打印生产高价值食品开辟了新的可能性.