[在急诊室的多抗菌株引起的尿路感染中使用抗菌素管理计划]
J Ruiz-Ramos1, S Herrera-Mateo, M A Rivera-Martínez
1Jesús Ruiz. Servicio de Farmacia. Hospital Santa Creu i Sant Pau. Barcelona, Spain. jrzrms@gmail.com.
概括
一个新的多学科计划优化了在急诊室治疗多耐药性尿路感染 (UTI) 的抗生素治疗. 这一举措减少了30天的再访,显示了改善患者结果和减少医疗保健负担的潜力.
科学领域:
- 传染性疾病 传染性疾病
- 临床药房 临床药房
- 紧急医疗 紧急医疗
背景情况:
- 尿路感染 (UTI) 是急诊室 (ED) 访问的常见原因之一.
- 多药耐药 (MDR) 细菌使尿路感染治疗复杂化,这给临床带来了重大挑战.
- 在ED中优化抗生素治疗对于管理MDR-UTI至关重要.
研究的目的:
- 评估一项多学科计划对在ED治疗的MDR-UTI患者的抗生素治疗的影响.
- 评估该计划在优化抗生素选择和减少随后医疗保健利用方面的有效性.
主要方法:
- 在一个涉及紧急情况,微生物学和药房部门的多学科计划上进行了一项描述性研究.
- 对从ED出院的MDR-UTI患者的抗生素治疗进行了审查.
- 干预措施包括联系医疗保健提供者或患者以优化治疗,结果以30天ED复诊率衡量.
主要成果:
- 在一年内,检查了2,474种尿液培养;其中533种 (21.7%) 涉及MDR细菌.
- 在53.4%的MDR-UTI病例中,经验性抗生素治疗是不适当的,在243名患者中进行了修改.
- 干预后30天的ED复诊率为19.3%,明显低于计划之前观察到的27.9% (p=0.031).
结论:
- 一个多学科计划有效地优化了MDR-UTI患者的抗生素治疗,这些患者从ED出院.
- 该计划显示了减少再入院和ED重访的潜力.
- 在ED排放层面优化抗生素管理是改善患者护理和资源利用的有价值策略.
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