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在小鼠中多重低剂量链毒素诱导糖尿病的剂量依赖性进展

Brandon M Bauer1,2, Supriyo Bhattacharya3, Elizabeth Bloom-Saldana1,4

  • 1Department of Molecular & Cellular Endocrinology, Arthur Riggs Diabetes & Metabolism Research Institute, City of Hope, Duarte, California, United States.

Physiological genomics
|July 17, 2023
PubMed
概括

不同的低剂量链毒素 (STZ) 独特地影响了小鼠的糖尿病发病和进展. 55毫克/千克的剂量引起了快速的葡萄糖不耐受,而35毫克/千克的剂量显示出明显的β细胞基因表达变化.

关键词:
贝塔细胞质量 贝塔细胞质量过高血糖的粘合剂胰岛素分泌的胰岛素分泌.翻译学 翻译学 翻译学 翻译学

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