在接受SARS-CoV-2 mRNA疫苗接种后,严重的低血与意识障碍
Takuya Kumagai1, Syohei Koyama2, Haruka Yorozu3
1Postgraduate Clinical Training Center, Akita Red Cross Hospital, Akita, Japan.
Endocrinology, diabetes & metabolism case reports
|July 17, 2023
概括
严重的低血,一种不适当的抗尿素激素分泌 (SIADH) 的情况,可在COVID-19 mRNA疫苗接种后发生. 对于接种疫苗后出现恶心和头痛等症状的患者来说,及时治疗至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 疫苗学 疫苗学 疫苗学
- 神经学 神经学
背景情况:
- 在COVID-19疫苗接种后,很少报告不适当的抗尿素激素分泌综合征 (SIADH).
- 低血症可以表现为恶心,吐和头痛等症状.
研究的目的:
- 在 SARS-CoV-2 mRNA 疫苗接种后,向 SIADH 报告严重的二次性低血症病例.
- 强调在接种疫苗后出现神经症状的患者考虑SIADH的重要性.
主要方法:
- 一个84岁的老妇人的病例报告.
- 记录了临床表现,实验室发现 (血含量) 和治疗干预措施.
- 在没有其他致病因素的情况下,确立了SIADH的诊断.
主要成果:
- 患者在第二剂SARS-CoV-2mRNA疫苗接种后出现严重的低血症 (血119 mmol/L).
- 最初用静脉注射盐水治疗显示出有限的改善.
- 服用3%盐溶液使血度正常化 (132 mmol/L),并缓解了症状.
结论:
- 本案例表明,SARS-CoV-2 mRNA疫苗接种与SIADH的发展之间可能存在关联.
- 临床医生应在COVID-19疫苗接种后出现神经症状的患者中保持对低血量,特别是SIADH的高度怀疑指数.
- 意识到这种潜在的不良影响对于及时诊断和管理至关重要.
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