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高强度的第一个近红外辐射通过能量迁移在多层上转化纳米粒子中的能量迁移

Xuegang Zheng^1,2, Ying Chen^1,2, Meijuan Liu^1,2

¹School of Physics and Materials Science, Guangzhou University, Guangzhou 510006, P. R. China. linhao@gzhu.edu.cn.

Physical chemistry chemical physics : PCCP

|July 17, 2023

概括

开发 (Tm³⁺) 807nm第一个近红外 (NIR-I) 发射与第二次近红外 (NIR-II) 激发对于生物医学应用至关重要. 这项研究介绍了新的多层核心外上转换纳米粒子 (UCNPs),其增强的NIR-I发射用于生物成像.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物医学工程生物医学工程

背景情况:

开发高效的上转化纳米粒子 (UCNPs) 用于生物医学应用需要精确控制它们的光学特性.
近红外 (NIR) 辐射对于生物成像中深层组织透特别有价值.

研究的目的:

使用NIR-II激发合成多层核心UCNP,以获得高效的807nmNIR-I发射.
为了研究Yb³⁺度对上转换发光效应的影响.
为了证明这些UCNP在生物成像中的潜力.

主要方法:

合成NaErF₄:Yb@NaYF₄:Yb@NaYF₄:Yb,Tm@NaYF₄多层核心外UCNP的联合沉方法.
调整Yb³⁺度在核心和第一个外,以优化上升转换的排放.
光学特性和向上转换机制的表征.

主要成果:

在1532nm激发下,从Tm³⁺获得高强度NIR-I发射 (807nm) 和从Er³⁺获得可见光.
证明了高效的能源迁移和反向传输过程.
与双层结构相比,多层核心外UCNP表现出优越的光学性能.

结论:

开发的多层核心外UCNP显示出生物成像的巨大潜力,因为它们在NIR-II激发下具有强烈的807nmNIR-I发射.
优化Yb³⁺度是提高上转效率的关键.
这些UCNP为体内应用提供了优势.

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