韩国的自愿输血受体注册作为血液组抗体的数据库
Dong Woo Shin1, Yun Ji Hong1,2, Jungwon Hyun3
1Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Blood transfusion = Trasfusione del sangue
|July 17, 2023
概括
韩国 韩国 韩国 韩国
科学领域:
- 输血医学 输血医学
- 免疫学 免疫学 免疫学
- 血液学 血液学 血液学
背景情况:
- 已建立的输血注册表旨在提高患者安全和血液银行效率.
- 自2013年7月以来,韩国已经运营了一个血液组抗体数据库和参考实验室.
- 这项研究评估了韩国目前血液组抗原和抗体的现状.
研究的目的:
- 确定韩国血液组抗原和抗体的现状.
- 为输血药物注册表提出一个模型.
- 使用注册数据分析抗体和抗原频率.
主要方法:
- 从自愿的在线输血注册 (2013年7月 - 2022年6月) 中收集的数据.
- 从29家医院注册了9,048例意想不到的红细胞抗体.
- 使用血液信息共享系统计算了抗原负频率并分析了RhCE抗原频率.
主要成果:
- 抗E是最常见的抗体,其次是抗E/c,抗C/e,抗Lea和抗M.
- 抗原阴性红细胞的频率为E- (49.1%),E-c- (41.6%),C-e- (9.1%),Le(a-) (69.4%) 和M- (21.8%).
结论:
- 输血注册有效估计了抗体和抗原分布.
- 抗原频率是从红细胞成分类型数据中得出的.
- 在线注册表作为流行病学研究的宝贵血型抗体数据库.
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