使用R进行基于试验的经济评估:一个教程
Ângela Jornada Ben1, Johanna M van Dongen2, Mohamed El Alili2
1Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, The Netherlands. a.jornadaben@vu.nl.
PharmacoEconomics
|July 17, 2023
概括
本教程为使用统计方法处理基于试验的经济评估中常见的挑战提供了指导,例如缺失的数据和扭曲的成本/效应. 它提供了一个R脚本来改进成本效益分析和医疗保健资源分配.
科学领域:
- 卫生经济学 卫生经济学
- 生物统计学 生物统计学
- 临床试验分析
背景情况:
- 基于试验的经济评估对于医疗保健决策至关重要.
- 常见的挑战包括缺失的数据,相关的成本/效应,基线不平衡和歪曲的数据.
- 有效性研究的现有方法可能不直接适用于联合成本效益分析.
研究的目的:
- 为基于试验的经济评估提供有关统计方法的逐步指导.
- 同时应对多个方法挑战.
- 提高医疗保健决策的证据质量.
主要方法:
- 结合适当的统计方法来处理缺失的数据,相关的成本/影响,基线失衡和偏差.
- 使用准备好使用的R脚本进行实际应用.
- 以模拟试验为基础的经济评估来说明方法.
主要成果:
- 该教程展示了如何整合统计技术来解决经济评估中复杂的方法问题.
- 为实际实施提供了一个R脚本.
- 应用程序使用模拟数据进行说明.
结论:
- 适当的统计方法至关重要,以避免基于试验的经济评估存在偏见.
- 这些指导和R脚本可以提高成本效益分析的可靠性.
- 改进的证据质量支持医疗保健资源的有效分配.
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