通过设计的质量 (QbD) 方法来开发使用 dispersion 与表面吸附方法配对的快速溶解片:flurbiprofen dispersion颗粒的配方和药理动力学

Sateesh Kumar Vemula1,2, Bhaskar Daravath3, Michael Repka4,5

  • 1Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA. svemula@olemiss.edu.

概括

这项研究使用散和表面吸附方法开发了快速溶解的flurbiprofen片. 与传统药片相比,这种新型配方显著改善了药物的溶解和生物可用性.

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