抗生素治疗成功后,与复发性尾炎相关的因素
1Surgical Outcomes Research Center, Department of Surgery, University of Washington, Seattle, Washington, USA.
The British journal of surgery
|July 17, 2023
概括
发作时恶心,吐或厌食症可能会增加尾炎抗生素治疗后尾切除的风险. 然而,尾炎或成像发现等因素与后期手术没有很强的联系.
科学领域:
- 胃肠病学 胃肠病学
- 外科手术的结果
- 传染性疾病 传染性疾病
背景情况:
- 对尾炎的抗生素使用越来越多,需要了解复发因素.
- 有信息的预后和决策对于个性化患者护理至关重要.
研究的目的:
- 为了确定与尾炎初始抗生素治疗后尾切除术的长期风险相关的基线患者因素.
- 为了比较经过尾切除术的患者和没有经过尾切除术的患者之间的结果,在30天至1年后进行抗生素治疗.
主要方法:
- 使用抗生素药物和尾切除试验结果比较数据的队列研究.
- 边际逻辑回归模型被用来计算调整后的风险差异 (RDs).
- 分析的重点是用抗生素治疗的患者,这些患者在30天内没有接受尾切除术.
主要成果:
- 在601名患者中,有144名患者 (23.9%) 接受了30天至1年间的尾切除术;56名患者在随访期间失踪.
- 尾切除术的增加率与基线恶心,吐或厌食症有关 (调整RD 17.52).
- 尾炎的存在或成像检测结果 (,穿孔,脂肪脱落) 与晚期尾切除并没有强烈相关.
结论:
- 通常与尾炎严重程度相关的因素在抗生素治疗后与长期尾切除风险的联系有限.
- 恶心,吐或厌食症是需要更密切监测或替代治疗策略的潜在指标.
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