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Updated: Jul 8, 2026

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在布鲁塞拉基因组中使用Dap-seq扫描铁反应调节器结合位

Huan Zhang1,2, Tianhao Sun1,2, Xudong Cao2,3

  • 1School of Animal Science and Technology, Shihezi University, Shihezi City, Xinjiang, China.

PLoS neglected tropical diseases
|July 17, 2023
PubMed
概括

铁反应调节器 (Irr) 控制布鲁塞拉的生长和铁的吸收. 这项研究确定了六种参与铁代谢的新型Irr调节基因,包括 rirA,这对布鲁塞拉铁的利用和生长至关重要.

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Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...