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Updated: Jul 23, 2025

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
11:02

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Published on: September 14, 2018

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对抗HER2单域抗体的联合结晶和人性化,作为一个神经学工具

Kovilen Sawmynaden1, Nicholas Wong2, Sarah Davies1

  • 1LifeArc, Open Innovation Campus, Stevenage, United Kingdom.

PloS one
|July 17, 2023
PubMed
概括

研究人员开发了NM-02,一种人性化的抗HER2单域抗体,用于乳腺癌治疗. 这种抗体向HER2,显示出对HER2阳性癌症的成像和潜在治疗应用的前景.

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Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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相关概念视频

Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
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