古代脊椎动物的皮肤盔甲是从干部神经顶进化而来的
Jan Stundl1,2, Megan L Martik1, Donglei Chen3
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
概括
神经细胞,起源于干部,形成骨的盔甲在斯特雷特的皮肤盔甲. 这一发现表明神经细胞在脊椎动物骨进化中的早期作用更广泛.
科学领域:
- 进化发育生物学 进化发育生物学
- 脊椎动物的古生物学
- 骨生物学 骨生物学
背景情况:
- 骨头是一种定义脊椎动物的创新,可能起源于祖先的皮肤盔甲.
- 这个早期骨的发育起源 (中皮与神经) 仍在争论中.
研究的目的:
- 为了研究非最远的光鱼的骨性皮肤护甲的发育起源.
- 为了追踪的骨质细胞的血统.
主要方法:
- 在活体中追踪鱼 (Acipenser ruthenus) 的血统.
- 护甲和的转录造型.
- 鱼皮肤护甲的组织学和微CT分析.
主要成果:
- 斯特莱特干神经细胞被明确地证明可以在骨中产生骨质母细胞.
- 一个神经基因的签名被识别在斯特莱特和比希尔.
- 射鱼的皮肤盔甲包括骨,牙和矿化组织,类似于早期脊椎动物的盔甲.
结论:
- 支持早期脊椎动物中神经细胞的原始,全身骨架性作用.
- 表明神经对皮肤盔甲的贡献在进化过程中逐渐局限于头部.
- 突出神经作为皮肤护甲多样化的关键进化驱动器.
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