血液学参数在高血压中的预测作用
Xiangzhu Meng1, Hong Sun2, Xiaowen Tu1
1Department of Cardiology, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, Jiangxi, China.
Angiology
|July 17, 2023
概括
新的血液学参数可以帮助预测高血压 (HT) 和其并发症. 这些廉价的标记物,包括中性粒细胞与淋巴细胞比率 (NLR) 和全身免疫炎症指数 (SII),为早期查和患者管理提供了宝贵的见解.
科学领域:
- 心血管医学 心血管医学
- 血液学 血液学 血液学
- 炎症研究 炎症研究
背景情况:
- 高血压 (HT) 是一个主要的全球健康问题,与目标器官损伤和心血管死亡率有关.
- 炎症越来越被认为是HT发展和进展的关键因素.
- 传统的HT炎症标志物通常比常规血液检测更昂贵,更难获得.
研究的目的:
- 审查高血压新型血液学参数的诊断和预后价值.
- 评估NLR,MHR,RDW,PLR,MPV,PDW和SII等参数作为HT的生物标志物的实用性.
主要方法:
- 在PubMed和Embase数据库中进行全面的文献搜索,截至2022年9月18日.
- 对调查血液学参数与高血压之间的关联的研究进行分析.
- 专注于反映炎症和血小板激活的参数.
主要成果:
- 一些血液学参数,包括中性粒细胞与淋巴细胞的比率 (NLR),单细胞与高密度胆固醇的比率 (MHR),红细胞分布宽度 (RDW),血小板与淋巴细胞的比率 (PLR),平均血小板体积 (MPV),血小板分布宽度 (PDW) 和全身免疫炎症指数 (SII),显示出HT生物标志物的潜力.
- 这些参数很容易从例行血液检查中获得,并且具有成本效益.
- 证据表明,它们在预测HT诊断和预后方面具有实用性.
结论:
- 血液学参数为早期高血压查和风险分层提供了一个有希望的,可访问的方法.
- 这些生物标志物可以帮助优化高血压患者的管理策略.
- 对这些参数的进一步研究可以提高心血管疾病的预防和治疗.
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