酒精隔膜切除在75岁或以上的患有多变性阻塞性心肌病的患者中
Dennis Lawin1, Christoph Stellbrink2, Ekaterina Stellbrink2
1Department of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, Bielefeld, Germany dennis.lawin@klinikumbielefeld.de.
Heart (British Cardiac Society)
|July 17, 2023
概括
酒精隔膜切除 (ASA) 是有效的老年患者高增多性阻塞性心肌病 (HOCM). 虽然疗效和死亡率与年轻患者相似,但老年人患AV阻塞率更高,需要起器.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 老年医学 老年医学
背景情况:
- 增高阻塞性心肌病 (HOCM) 可以显著影响生活质量.
- 酒精隔膜切除 (ASA) 是HOCM的治疗选择,但对老年患者 (≥75岁) 的数据有限.
研究的目的:
- 为了评估75岁及以上的HOCM患者ASA的结果.
- 为了比较ASA在老年患者和年轻患者的疗效和安全性.
主要方法:
- 对1997年9月至2021年7月期间连续执行的ASA程序进行回顾性分析.
- 纳入标准:HOCM的左心室外流通道梯度 (LVOTG) ≥50 mm Hg.
- 在基线和6个月随访时,患者≥75岁和<75岁之间的心声学,程序和临床参数的比较.
主要成果:
- 在75岁以上的患者中进行了208次ASA,在75岁以下的患者中进行了1430次.
- 75岁以上的患者表现出较低的基线6分钟步行测试距离 (317.0m vs 438.0m).
- 随访LVOTG在老年人群中较低 (29.5 mm Hg vs 39.5 mm Hg),但高度AV阻塞率较高 (25.5% vs 13.6%). 住院死亡率相似 (1.0%对0.6%).
结论:
- 与年轻人相比,ASA证明了与HOCM患者的老年患者 (≥75岁) 的可比疗效和住院死亡率.
- 接受ASA治疗的老年患者患上高度心房静脉阻塞的风险增加,需要永久植入心脏起器.
关键词:
心肌病,高性心肌病,高性心肌病.更多相关视频
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