日本中风亚型的风险和人口可归因的比例
Hiroshi Yatsuya1, Kazumasa Yamagishi2, Yuanying Li1
1Department of Public Health and Health Systems, Nagoya University Graduate School of Medicine.
Journal of epidemiology
|July 17, 2023
概括
高血压是日本中风预防的主要可修改风险因素,显著增加了中风风险. 治疗高血压,吸烟和糖尿病可以减少整体中风发生率.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 心血管疾病研究研究
背景情况:
- 缺乏对主要中风风险因素及其人口归因分数 (PAFs) 的全面分析.
- 了解这些关联对于有针对性的中风预防策略至关重要.
研究的目的:
- 检查主要风险因素与总中风,中风类型和缺血性中风亚型的关联.
- 估计这些风险因素的人口归因分数 (PAFs).
主要方法:
- 展望性队列研究 (JPHC研究队列II) 与14,797名参与者进行了20年的跟踪.
- 相互调整的考克斯回归模型评估了吸烟,高血压,糖尿病,超重,胆固醇,尿蛋白和心律失常的相关性.
- 使用危险比率和风险因素流行率来计算PAF.
主要成果:
- 高血压使任何中风的可能性增加了1.631.84倍.
- 吸烟,糖尿病,低HDL胆固醇,超重,尿蛋白和心律失常与整体和缺血性中风有关.
- 高血压是主要的风险因素,占中风发病率的25%以上,其次是吸烟和糖尿病.
结论:
- 高血压被确定为日本中风预防的最关键目标.
- 组合可修改的风险因素对中风发病率有显著的贡献,特别是大动脉封闭性中风.
更多相关视频
04:38A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
10.3K
09:11Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
Published on: February 23, 2016
21.9K
相关概念视频
Regulation of Stroke Volume
3.3K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.3K
Relative Risk
225
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
225
Ischemic Heart Disease: Overview
1.3K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K
Prevalence and Incidence
634
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
634
Coronary Artery Disease IV: Preventive Measures
25
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
25
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
148
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148
