大型动物体外血管植入式心脏转换器-除器系统感染
Amy E Thompson1, Melissa Christie1, Linnea Lentz1
1Medtronic, Inc.
International heart journal
|July 17, 2023
概括
大型动物的血管外植入式心脏转换器-除器 (EV ICD) 感染可以通过系统切除和抗生素治疗. 仅用抗生素治疗的感染并没有消失,与用系统扩散和抗生素治疗的感染不同.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医疗器械 医疗器械
背景情况:
- 外血管植入式心脏转换器-除器 (EV ICD) 与传统系统相比,具有潜在的临床益处.
- 表面感染是一种潜在的并发症,但其在EV ICD系统中的管理仍未得到充分探索.
研究的目的:
- 为了研究植入EV ICD系统的大型动物的下感染.
- 评估EV ICD相关感染的治疗策略.
主要方法:
- 在13只大型动物 (狗,猪,羊) 中植入了EV ICD系统.
- 诱导感染,并对动物进行12-18周的监测.
- 感染被单独用抗生素治疗或用系统去除加上抗生素治疗.
主要成果:
- 发生了四例EV ICD感染;仅用抗生素治疗的两例没有得到解决.
- 两个EV ICD感染用抗生素治疗和系统去除得到解决.
- 没有EV ICD感染进展到血液感染或骨骨质炎.
结论:
- 与EV ICD相关的感染可以通过手术和抗生素治疗来治疗.
- 系统删除对于解决EV ICD感染至关重要.
关键词:
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