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Updated: Jul 23, 2025

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
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桃体状细胞癌的甲状腺内转移,伪装成一次性甲状腺瘤
1Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.
Journal of pathology and translational medicine
|July 17, 2023
概括
从桃体状细胞癌的甲状腺内转移是罕见的. 这一案例强调了甲状腺扩大作为诊断初级桃体癌之前的初始症状.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 桃体状细胞癌的甲状腺内转移是一个不常见的现象,以前只有六例病例被记录.
- 甲状腺转移可以潜伏地呈现,有时在诊断初级恶性瘤之前.
研究的目的:
- 报告一种罕见的人类乳头瘤病毒阳性桃体状细胞癌的甲状腺内转移病例.
- 为了强调在诊断初级桃体瘤之前,扩散性甲状腺扩大的不寻常的初始呈现.
主要方法:
- 甲状腺组织的组织病理学检查,包括p40和p16的免疫组织化学检查.
- 聚子发射断层扫描-计算机断层扫描 (PET-CT) 用于分期和定位.
- 桃体区域的活检用于确定诊断.
主要成果:
- 患者出现了扩散性甲状腺扩大,最初怀疑是甲状腺原发性瘤.
- 组织学揭示了在甲状腺副体内广泛的内淋巴瘤栓塞,与转移一致.
- PET-CT在桃体区域发现了高代谢活动,导致活检确认了人类乳头瘤病毒阳性状细胞癌.
- 甲状腺炎背景显示慢性淋巴细胞变化.
结论:
- 这一病例是第一个报告的桃体状细胞癌的甲状腺内转移病例,最初呈现甲状腺扩大.
- 这些发现强调了在甲状腺质量的差异诊断中考虑甲状腺外原发性瘤的重要性,特别是在有暗示性成像和临床发现的情况下.
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