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Updated: Jul 23, 2025

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检查点抑制剂PD-1H/VISTA可以控制骨质细胞介导多发性骨髓瘤骨疾病

Jing Fu1, Shirong Li1, Huihui Ma1,2

  • 1Columbia University Irving Medical Center, Department of Medicine, New York, NY, USA.

Nature communications
|July 17, 2023
PubMed
概括

研究人员在多发性骨髓瘤骨病中发现编程死亡-1同源 (PD-1H) 作为矩阵金属蛋白酶13 (MMP-13) 的受体. 针对这个MMP-13/PD-1H轴,可以治疗骨解性骨病变.

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