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Updated: Jul 23, 2025

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代谢比率和SNP与特拉马多尔相关的死亡有关

Sanaa M Aly1,2, Florian Hakim3,4, Camille Richeval3,4

  • 1Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt. sasydayem@hotmail.com.

International journal of legal medicine
|July 17, 2023
PubMed
概括

在CYP2D6,CYP2B6和CYP3A4的遗传变异影响了特拉马多尔 (TR) 的代谢. 特定的多态性与改变的代谢比率相关,并可能增加TR毒性的风险,特别是在过量服用的情况下.

关键词:
在CYP2B6B6中.在CYP2D6中.在 CYP3A4 中.法医毒理学 法医毒理学这是下一代测序.在死后进行尸检.

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