新生儿复苏器中强加的阻力对压力稳定性和峰值流量的影响:一个实验室测试
Kristel L A M Kuypers1, Aidan J Kashyap2,3, Sophie J E Cramer4
1Division of Neonatology, Department of Paediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Centre, Leiden, The Netherlands. k.l.a.m.kuypers@lumc.nl.
Pediatric research
|July 17, 2023
概括
新生儿复苏器耐药性影响呼吸. 与NeopuffTM系统相比,r-PAP的阻力较低,产生更稳定的压力和更高的峰值流量.
科学领域:
- 新生儿护理 新生儿护理
- 呼吸系统生理学 呼吸系统生理学
- 医疗器械工程 医疗器械工程
背景情况:
- 新生儿复苏器中耐药性的临床意义尚不清楚.
- 本研究评估了不同阻力对正压通风 (PPV) 和模拟自发呼吸 (SSB) 的影响.
研究的目的:
- 为了比较两个新生儿复苏器的峰值流量和压力稳定性:r-PAP (低阻力) 和NeopuffTM (高阻力).
- 为了研究不同偏差气体流量设置对复苏器性能的影响.
主要方法:
- 对于每个设备,PPV期间进行20次膨胀和SSB期间进行20次呼吸的长椅测试.
- 在不同偏差气体流量下分析峰值流量和压力稳定性 (NeopuffTM 的8,12,15 L/分钟;r-PAP 的15 L/分钟).
主要成果:
- 在NeopuffTM上增加偏向气流减少了PPV和SSB期间的阻力和增加了峰值流量.
- 与NeopuffTM相比,r-PAP在SSB期间始终表现出较高的峰值流量和较小的CPAP波动.
- 在PPV期间,在r-PAP中发现了3.2cmH2O的压力超标.
结论:
- r-PAP复苏器的强加阻力比NeopuffTM T-piece系统要低.
- 像r-PAP这样的较低阻力装置提供更稳定的CPAP和更高的峰值流量.
- 在传统的T片系统上优化偏差流量可能会平衡阻力降低,并限制新生儿潜在有害的高峰流量.
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