同时发生的大动脉反预测,在经过透气管大动脉置换后,左心室逆向重塑会更好
Hao-Ran Yang1, Tian-Yuan Xiong1, Yi Zhang1
1Department of Cardiology and Laboratory of Heart Valve Disease, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, PR China.
BMC cardiovascular disorders
|July 17, 2023
概括
研究了通过导管大动脉置换 (TAVR) 后左心室质量指数 (LVMi) 回归不足的预测因素. 在基线时超过轻度的大动脉反 (AR) 可能预测TAVR后更好的LVMi回归.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 干预心脏病学 干预心脏病学
背景情况:
- 左心室质量指数 (LVMi) 回归是跨导管大动脉置换 (TAVR) 后成功结果的关键指标.
- 脊心脂肪组织 (EAT) 的特征可能会影响TAVR后的心脏重塑.
- 低最佳LVMi回归的预测因素需要进一步阐明.
研究的目的:
- 在TAVR后的中期随访中确定不充分的LVMi回归的预测因素.
- 评估心上脂肪组织 (EAT) 在TAVR后LVMi回归中的作用.
主要方法:
- 一年后对152名接受TAVR的患者进行回顾性审查,并提供心声回声和多切片计算机断层扫描 (MSCT) 数据.
- 从基线到一年的LVMi变化,EAT体积和EATCT衰减的计算.
- 基于LVMi回归百分比的组比较 (≥15%与<15%).
主要成果:
- 在TAVR后,LVMi显著下降 (P<0.0001),而EAT体积增加,CT衰减下降 (P<0.0001).
- 基线因子在各组之间有所不同,包括心房动,心肌流 ≥轻度,大动脉流 (AR) >轻度,以及EAT CT衰减的变化.
- 在多变量分析 (OR 0.33,P=0.021) 中,在基线时超过轻度的AR是不足的LVMi回归 (<15%下降) 的唯一显著预测因素.
结论:
- 同时出现轻度以上的大动脉反 (AR) 可能与TAVR后左心室逆转型改造回归更好相关.
- 这些发现强调了基线AR严重程度在预测TAVR结果方面的重要性.
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