疼痛的颗粒状的哈希莫托甲状腺炎揭露了系统性血清质症
Nicholas Polster1, Bianca Puello Yocum1, John-Paul Lavik1
1Department of Laboratory Medicine & Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
International journal of surgical pathology
|July 18, 2023
概括
本病例报告详细介绍了一例罕见的同时发生的哈西莫托和质体甲状腺炎的例子,该病例发生在一个免疫能力强的个体中. 早期诊断和治疗真菌甲状腺炎对于预防严重后果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 颗粒状甲状腺炎通常是病毒性;真菌感染很少见,主要影响免疫力低下的人.
- 在免疫能力较强的患者中,真菌性甲状腺炎并不常见.
- 哈西莫托甲状腺炎是一种影响甲状腺的自身免疫性疾病.
研究的目的:
- 在一个免疫能力强的患者中报告一种罕见的同时出现的哈西莫托病和质体甲状腺炎病例.
- 突出诊断挑战和治疗的真菌甲状腺炎.
- 强调认识到真菌甲状腺炎作为系统性感染的重要性.
主要方法:
- 一个病例报告,一名32岁的男性患有哈希莫托甲状腺炎,出现甲状腺功能障碍症状.
- 诊断程序包括成像,实验室测试,甲状腺叶切除术与组织病理学,和血清学.
- 治疗涉及口服伊特拉科纳.
主要成果:
- 组织病理学揭示了与甲状腺中的细胞质相一致的颗粒瘤和酵母.
- 血清学测试证实了西托等离子体感染.
- 该患者具有免疫能力,没有发现免疫缺陷.
- 用伊特拉可纳治疗导致宪法症状的解决.
结论:
- 同时的哈西莫托氏和质体甲状腺炎在免疫能力强的个体中异常罕见.
- 系统性真菌感染症状可以被甲状腺功能障碍症状掩盖.
- 性甲状腺炎需要及时的全身抗真菌治疗,以避免严重的并发症和死亡.
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