一种在前列腺癌中抑制糖解的化合物控制了晚期前列腺癌的生长

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Updated: Jul 23, 2025

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

Published on: December 26, 2016

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Takuma Uo, Kayode K Ojo, Cynthia C Sprenger

    bioRxiv : the preprint server for biology
    |July 18, 2023
    PubMed
    概括

    一个新的小分子,BKIDC-1553,抑制了hexokinase 2,这是前列腺癌糖解中的关键酶. 这种临床前候选药物显示出有前途的安全性和疗效,支持其进入转移性割抵抗性前列腺癌临床试验的进展.

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