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Updated: Jul 23, 2025

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
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在低于最佳条件下的 CaaX 动机相邻残留物控制 G 蛋白质前化

Mithila Tennakoon1,2,3, Waruna Thotamune1,2,3, John L Payton4

  • 1Department of Chemistry, Saint Louis University, Saint Louis, MO 63103, USA.

bioRxiv : the preprint server for biology
|July 18, 2023
PubMed
概括

根据特定的碳氧末端残留物,他类药物对G蛋白玛子单元预基化有不同的影响. 这解释了他类药物如何影响细胞信号传递,并可能为向前化蛋白的癌症疗法提供信息.

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