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Updated: Jul 23, 2025

Monitoring Leucine-Rich Repeat Containing 8 Channel (LRRC8/VRAC) Activity Using Sensitized-Emission Förster Resonance Energy Transfer (SE-FRET)
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Monitoring Leucine-Rich Repeat Containing 8 Channel (LRRC8/VRAC) Activity Using Sensitized-Emission Förster Resonance Energy Transfer (SE-FRET)

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对心脏瑞诺丁受体FRET生物传感器的分子机制 病理性泄漏状态

Bengt Svensson1, Florentin R Nitu1, Robyn T Rebbeck1

  • 1Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis.

bioRxiv : the preprint server for biology
|July 18, 2023
PubMed
概括

DPc10和calmodulin (CaM) 与泄漏的心脏氨酸受体 (RyR2) 相互作用. DPc10调节了CaM与RyR2的结合,为针对心律失常的药物发现提供了洞察力.

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